Tuesday, June 1, 2010

Prolia (Denosumab) Approved in Europe For Osteoporosis

Amgen has acquired FDA approval for Denosumab to sell in Europe. Last stage trial of Denosumab is expected to finish soon and may get approval for USA market too. Prolia is propsed brand name of Denosumab. Amgen will team up GlaxoSmithKline to start commercial production of the drug.
Like other best inventions Denosumab also discovered by accident while scientists were performing experiments on mice at Amgen's lab. A mice grew up big when an experiment, related to gene disabling research, was performed on it. Scientists observed remarkable growth of mice bones.

Europe FDA has approved Denosumab for the treatment of osteoporosis medications. The drug is talk of the town in biomedical industry for its strong effects. Experts believe it to be the best medication ever produced for patients who are at high risk of fractures caused by bone disease. Denosumab can also be used by women in post-menopausal and prostate cancer patients.

Amgen is focused on development of new treatment for bone diseases such as osteoporosis. It is during the part of one such research when they found this drug. Denosumab works by preventing a specific protein that is responsible for bone related diseases. Prolia selectively targets RANK Ligand, a protein, that regulates osteoclasts cells. Prolia reduces the risk of fracture through a convenient injection given every six months. In USA, this drug is most waited drug in pharmaceutical market.

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